Dipalmitoylphosphatidylcholine (DPPC) is a synthetic phospholipid. As an excipient, it is a major component of biological membranes, and due to its bilayer structure's ability to encapsulate drug molecules, it is also a common component of liposomal drug delivery systems. As an active ingredient (API), it is primarily present in exogenous pulmonary surfactants.
| Product Name | 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine(for injection) DPPC |
| Chemical Name | / |
| CAS No. | 63-89-8 |
| NMPA CDE registration no. | F20180000192 |
| USFDA DMF No. | 19820 |
| Quality grade | Injection |
| Quality standards | Manufacturer's standard |
| Molecular Formula | C40H80NO8P |
| Applications and examples | Amikacin liposome inhalation suspension, Surfaxin intratraqueal suspension |
| Product code | S01004 |
| Package sizes | 1kg |
| Storage condition | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
We supply DPPC with a high purity of over 99%;
Because the fatty acids used to prepare DPPC can be customized, various DPPC molecules with controllable phase transition temperatures can be obtained;
DPPC is also a major component of pulmonary surfactants for respiratory distress syndrome management;
DPPC exhibits unparalleled biocompatibility and safety compared to other synthetic phospholipids;
And it is also the preferred phospholipid and a primary component of liposomal inhalers.
DPPC is an endogenous substance in the human body and is one of the main components of the human pulmonary surfactant, accounting for over 60% of the total. It is distributed on the surface of the liquid layer lining the alveolar space and serves to reduce alveolar surface tension, maintaining the relative stability of alveolar volume while preventing fluid from leaking into the alveoli from pulmonary capillaries. Because DPPC is one of the natural phospholipid components of the alveoli, it possesses biological compatibility and safety that other synthetic phospholipids lack.
If you have any questions, please don't hesitate to contact us. We're always here to help with Pharmaceutical Excipients for your business. We can provide products ranging from grams to tons. AVT is able to produce and even register the product in US FDA according to your special needs.
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