Phosphatidylglycerol (PG) phospholipids carry a negative charge due to their negatively charged polar phosphate groups, rendering the entire molecule negatively charged. Depending on the fatty acid chains, common PG phospholipids such as dipalmitoylphosphatidylglycerol (DPPG) and dimyristoylphosphatidylglycerol (DMPG) show significant differences in phase transition temperatures.
NMPA CDE registration no.: F20180000838(A)
USFDA DMF no.: 032797
| Product Name | Dipalmitoyl Phosphatidylglycerole |
| Chemical Name | 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylglycerol (sodium salt) |
| CAS No. | 200880-41-7 |
| NMPA CDE registration no. | F20180000838 |
| USFDA DMF No. | 032797 |
| Quality grade | Injection |
| Quality standards | Manufacturer's standard |
| Molecular Formula | C38H74O10PNa |
| Applications and examples | This product is Dipalmitoyl Phosphatidylglycerole (for injection), a fully synthetic phospholipid. It is suitable for the preparation of anionic liposomes and is a common choice of negatively charged membrane materials. It also plays a key role in improving the stability of liposomes. It has been widely used in the R&D of liposome drugs and the prescriptions of marketed products, and has also been used in some liposome projects in clinical stages, e.g., Lipoplatin. |
| Product code | S02003 |
| Package sizes | 1g, 10g |
| Storage condition | The product should be transported at -20 ± 5℃. It should be stored at -20℃ in well-closed containers, protected from light. Avoid exposure to strongly oxidizing media. It should be retested every 12 months when used and stored properly. |
Phosphatidylglycerol (PG) phospholipids are widely used in preparation of liposomes;
Lipid particles with negative charges can prevent particle aggregation, thereby enhancing the stability of formulations;
Negatively charged lipid particles are more likely to penetrate cell membranes for delivery.
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