DMPA-Na is a phospholipid that can be formed through three synthetic pathways: First, the acylation of lysophospholipid acid; second, the phosphorylation of diacylglycerol; third, the removal of the choline group from phosphatidylcholine. In this process, long-chain (14:0) myristic acid is inserted into the sn-1 and sn-2 positions of the phospholipid molecule. DMPA-Na plays a crucial role in intracellular and extracellular signal transduction.
| Product Name | 1,2-Dierucoyl-sn-Glycero-3-Phosphate, DMPA |
| Chemical Name | 1,2-Dierucoyl-sn-Glycero-3-Phosphate |
| CAS No. | 80724-31-8 |
| NMPA CDE registration no. | / |
| USFDA DMF No. | / |
| Quality grade | Reagent |
| Quality standards | Manufacturer's standard |
| Molecular Formula | C31H60NaO8P |
| Applications and examples | Liposome |
| Product code | / |
| Package sizes | 1g, 10g, 50g |
| Storage condition | Please store the product under the recommended conditions in the Certificate of Analysis. |
1,2-Dimyristoyl-sn-glycero-3-phosphate sodium salt can be used to evaluate various phosphatidic acids in micelles, liposomes, and artificial membranes. Glycerophospholipids belong to a category of lipids that consist of glycerol and phosphoric acid esters. 1,2-Dimyristoyl-sn-glycero-3-phosphate sodium salt is a lipid present in various organisms. It possesses fluidity characteristics and can be enzymatically deactivated by chlorides. Antibiotics like fusidic acid target glycerophospholipids by binding to the phosphate groups on their surface. Specifically, the head group of the phosphoglyceride molecule, composed of one glycerol and two phosphate groups, serves as the molecular target for these antibiotics. This head group interacts with the bacterial cell membrane, inducing increased permeability to ions, ultimately leading to cell lysis.
DMPA-Na is a colorless crystalline solid, soluble in water and alcoholic solvents. It has excellent stability and can be highly purified.
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