Lysophosphatidylcholine (Lyso-PC) is a degradation product of lecithin. Generated through the hydrolytic action of enzymes such as phospholipase A1, phospholipase A2, and phospholipase B, it is a normal metabolic product of phospholipids in the human body. Depending on the cleavage site of the phospholipid ester bond, lysophosphatidylcholine can be classified into lysophosphatidylcholine 1 and lysophosphatidylcholine 2. Under normal conditions, due to steric hindrance (spatial obstruction within the molecular structure), the ratio of lysophosphatidylcholine 1 to lysophosphatidylcholine 2 in phospholipid products is approximately 1:9, with lysophosphatidylcholine 2 being predominant.
| Product Name | P-Lyso-PC |
| Chemical Name | 1-Palmitoyl-2-lyso-sn-glycero-3-phosphocholine |
| CAS No. | 17364-16-8 |
| NMPA CDE registration no. | / |
| USFDA DMF No. | / |
| Quality grade | Reagent |
| Quality standards | Manufacturer's standard |
| Molecular Formula | C24H50NO7P |
| Applications and examples | Lyso-PC exhibits significant surfactant properties and potent hemolytic activity, capable of causing the rupture of red blood cells and other cellular membranes, resulting in hemolysis or cell necrosis. |
| Product code | S06002 |
| Package sizes | 1kg |
| Storage condition | This product should be stored and transported in a light-protected and sealed container under freezing conditions. It should be kept away from strong oxidizing agents. When stored properly, it is valid for 24 months. |
1-Palmitoyl-sn-glycero-3-phosphocholine is an abundant lysophosphatidylcholine.
1-Palmitoyl-sn-glycero-3-phosphocholine exhibits proinflammatory activity.
1-Palmitoyl-sn-glycero-3-phosphocholine can be used in the study of atherosclerosis
Lyso-PC exhibits significant surfactant properties and potent hemolytic activity, capable of causing the rupture of red blood cells and other cellular membranes, resulting in hemolysis or cell necrosis. However, under normal physiological conditions, the presence and quantity of phospholipases are strictly regulated, ensuring that the organism is not harmed by Lyso-PC.
Appearance: white crystalline powder.
Solubility: freely soluble in alcohols, ether and chloroform, and slightly soluble in water.
Chemical structure: consisting of hexadecanoyl acid, glycerol and phosphocholine.
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