PC Phospholipid

liposomal Phospholipids are used as skeleton membranes of liposomes.

In the fields of biochemistry and pharmaceutical chemistry, DMPC is often used as an intermediate. It can be used in the synthesis of polypeptide-based drugs, vitamins, and phospholipids with specific...

The injection-grade DSPC supplied by V.A.T. is suitable for preparing liposomes and lipid nanoparticles (LNPs), serving as an excellent membrane material and helper lipid choice. DSPC has been extensively used in the development of liposomal drugs and LNPs, with relevant products already on the market and several liposomal drug products currently in clinical stages.

The injection-grade DOPC supplied by A.V.T. features high stability and purity, making it suitable for use as a membrane material in liposomes. Due to its lower phase transition temperature and susceptibility to oxidation owing to its double bond structure, its application is not as widespread as that of DSPC, HSPC, and others. However, it serves as a crucial excipient in many commercially available liposomal products, such as liposomal cytarabine, liposomal morphine sulfate, Epaxal, Inflexal V, and Shingrix.

When using cholesterol (CHO-HP) as an auxiliary emulsifier, different synthetic phospholipids can be chosen to meet the requirements of various drug components, enabling the preparation of liposomes w...

DPPC is a synthetic phospholipid with a purity of at least 98.0% and can be used as a lipid membrane material in the preparation of liposomes.DPPC is also an endogenous substance and is the main compo...