Tris (CAS number: 77-86-1, white crystalline) is a buffer salt widely used in the field of biomedicine. Its full name is Tris (hydroxymethyl) aminomethane. pKa at 25°C is 8.06. Commonly used in proteins or nucleic acid buffers. The effective pH range is usually between 7.0-9.2.
NMPA CDE registration no.: F20220000153
USFDA DMF no.: 037604
| Product name | Tris Base; Tromethamine |
| Chemical Name | Tris (hydroxymethyl) aminomethane |
| CAS No. | 77-86-1 |
| NMPA CDE registration no. | F20220000153 |
| USFDA DMF No. | 037604 |
| Quality grade | Pharmaceutical |
| Quality standards | Comply with ChP, USP, EP or other pharmacopoeia standards |
| Molecular formula | C4H11NO3 |
| Applications and examples | Monoclonal and bispecific antibodies, Antibody-drug conjugates (ADC), liposomes, nucleic acid drugs, vaccines and other premium preparation |
| Product code | A02011 |
Package sizes | 1kg |
Storage condition | It should be stored in well-closed containers at room temperature, protected from light. It is valid temporarily for 3 years when used and stored properly. |
Tris buffers are widely used and play an important role in biochemistry, molecular biology, in vitro diagnostics, cosmetics, coatings and other fields;
Produced in accordance with GMP guidelines and with strict microbial and endotoxin limits control;
Can be used in protein purification process;
Pharmaceutical grade without registration.
Tris base is highly alkaline, so this buffer system alone can be used to prepare buffer solutions with a wide range of pH values from acidic to alkaline;
It has very limited interference with biochemical processes and does not precipitate with calcium ions, magnesium ions and other heavy metal ions;
It's highly soluble in water and is inert to many enzyme reactions.
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