Tris (CAS number: 77-86-1, white crystalline) is a buffer salt widely used in the field of biomedicine. Its full name is Tris (hydroxymethyl) aminomethane. pKa at 25°C is 8.06. Commonly used in proteins or nucleic acid buffers. The effective pH range is usually between 7.0-9.2.
NMPA CDE registration no.: F20220000153
USFDA DMF no.: 037604
| Product Name | Tris Base; Tromethamine |
| Chemical Name | Tris (hydroxymethyl) aminomethane |
| CAS No. | 77-86-1 |
| NMPA CDE registration no. | F20220000153 |
| USFDA DMF No. | 037604 |
| Quality grade | Reagent |
| Quality standards | Comply with ChP, USP, EP or other pharmacopoeia standards |
| Molecular Formula | C4H11NO3 |
| Applications and examples | Monoclonal and bispecific antibodies, Antibody-drug conjugates (ADC), liposomes, nucleic acid drugs, vaccines and other premium preparation |
| Product code | A02011-1 |
| Package sizes | 1kg |
| Storage condition | It should be stored in well-closed containers at room temperature, protected from light. It is valid temporarily for 3 years when used and stored properly. |
Tris buffers are widely used and play an important role in biochemistry, molecular biology, in vitro diagnostics, cosmetics, coatings and other fields;
High purity, low iron ions, low chloride ions;
It can be used in scientific research experiments such as gel electrophoresis and Western blotting.
Tris base is highly alkaline, so this buffer system alone can be used to prepare buffer solutions with a wide range of pH values from acidic to alkaline;
It has very limited interference with biochemical processes and does not precipitate with calcium ions, magnesium ions and other heavy metal ions;
It's highly soluble in water and is inert to many enzyme reactions.
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